Atypical hub organization in epilepsy and hub mapping as a potential biomarker of cognitive dysfunction and postsurgical seizure outcome

Abstract

Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are brain regions with high connectivity to other parts of the brain and are typically situated along the brain's most efficient communication pathways, supporting large-scale brain wiring and many higher order neural functions.